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Alzheimer's Disease Biosea Health Heart Health

Healthy Heart Reduces Dementia

A recent study published in PLOS showed a healthy heart reduces dementia in a cohort of about 1500 Finish people. Improvements in heart health in midlife reduced dementia risk. It was the latest study finding people with better cardiovascular health metrics scores in midlife had a significantly lower risk of late-life dementia.

More than 5 million adults aged 65 years and older in the United States are predicted to have dementia, with projected increases to nearly 14 million people by 2050. In Australia, it affects about 1 in 15 over the age of 65. The cost is more than $15 billion and costs about $35,000 per sufferer. [4] It is not a “normal” part of aging. Lifestyle makes a big difference.

Severe cognitive dysfunction involving difficulties with memory, recognition, language, decision making, attention, and problem-solving accompanies dementia. This can interfere with a person’s daily functioning.

The Healthy Heart Reduces Dementia Study

Dementia is a long term disease and this cohort study included 1,449 participants from the Finnish Cardiovascular Risk Factors, Aging, and Dementia (CAIDE) study, who were followed from midlife (baseline from1972 to 1987; mean age 50.4 years; 62.1% female) to late life (1998), and then 744 dementia-free survivors were followed further into late life (2005 to 2008). (30 year study)

Outcomes

The dementia rate was about 3.8% over a 20-year cumulative incidence for a healthy heart regime. If you had an unhealthy profile the risk of increase of dementia by about 3 times (to 9% over those 20 years)

Some lifelong modifiable risk factors identified in epidemiological studies, including cardiovascular risk factors from mid to late life, play a crucial role in the onset and progression of dementia. Seaweed reduces blood pressure and decreases heart inflammation in animal studies.

In fact, simulation research estimates that up to 35% of dementia cases may be due to modifiable risk factors across the life span. These risk factors include social and mental health factors such as education, social engagement, hearing loss, and depression.

Epidemiological studies also show the importance of cardiovascular health in the prevention of dementia. Factors such as smoking, diabetes, heart failure, atrial fibrillation, high blood pressure, obesity, and high cholesterol are all associated with an increased risk of dementia.

The American Heart Association’s (AHA) has 7 cardiovascular health metrics and four are behavioral:

  • physical activity
  • diet
  • smoking
  • body weight

Three components are biological:

  • blood cholesterol
  • blood pressure
  • blood glucose

Scientists have associated having ideal cardiovascular health metrics in midlife with a reduced incidence of dementia in later life.

Seaweed Reduces Dementia

In animal studies seaweed reduces dementia – but the translation from lab to human use is not direct. However there is enough evidence that the models are sound. This study concluded a healthy heart reduces dementia and there is data that seaweed reduces hypertension and diabetes – both major risk factor to dementia.

Dementia

References

[1] Liang Y, Ngandu T, Laatikainen T, Soininen H, Tuomilehto J, Kivipelto M, et al. (2020) Cardiovascular health metrics from mid- to late-life and risk of dementia: A population-based cohort study in Finland. PLoS Med 17(12): e1003474. https://doi.org/10.1371/journal.pmed.1003474

[2] [1] Wanyonyi, S; du Preez, R; Brown, L; Paul, N; Panchal, S  2017 Kappaphycus alvarezii as a Food Supplement Prevents Diet-Induced Metabolic Syndrome in Rats. Nutrients (9) 11 DOI:10.3390/nu9111261 (Click for Abstract) (Click to download full paper)

[3] Bogie, J et al (Including Monique Mulder) 2019 Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model. Scientific Reports 9 (1) DOI 10.1038/s41598-019-41399-4 (Click for Abstract) (Click to download full paper)

[4] Dementia – an overview. Healthdirec facts https://www.healthdirect.gov.au/dementia-overview

Categories
Biosea Health Health Benefits Heart Health Seaweed for Humanity

Boost Immunity with Seaweed

The World Health Organization will soon declare a pandemic. Countries are preparing for the pandemic. Boost immunity with seaweed.

In our hugely complex global moment of change in transportation, economies, energy, we have an exogenous shock. A massive, tiny bundle of protein, the troublesome 120nm-diameter spiky virus. In its shell, is a wound-up pair of DNA strands, carrying just eight kilobytes of genetic code. It begins:

attaaaggtt tataccttcc caggtaacaa accaaccaac

Germs have changed the course of history in the past. Zoonotic transplants from crowded European towns, where humans lived cheek-by-jowl with their animals, were a powerful ally to the Spanish during the genocidal colonisation of South America. Bill Gates calls this latest a “once-in-a-century” pandemic.

 What makes this virus different from seasonal flu is how easily it spreads. Sheer numbers of people infected. Nursing homes, hospitals will be overwhelmed.  There is every chance that both you and I will come down with the disease. A broad guess is that 25-70% of the population of any infected country may catch the disease.

  • Young – the effects from disease are mild.
  • Elderly have a one chance in six of dying
  • Middle aged? The chances are less.
  • If “health compromised” i.e. have high blood pressure or diabetes your chances of dying have more than doubled

Check out the graphs from WHO below.

Importantly, if you suffer from other medical conditions, like hypertension or diabetes, then you can make some small but important changes.

Boost Immunity with seaweed

 Now is the time to prepare.  Prepare your body with a boost to your immunity.  And prepare for some interruption as the government imposes the only thing it can at this stage which is movement control. So prepare to be at your home for a couple of weeks, with children and not being able to go to work.

Boost Immunity and Eat Seaweed

What can you do to boost your immunity to a virus? Taking seaweed is the quickest and easiest option. Stop smoking. Eat healthy

1. If you are over 70

  • Improve your heart health with seaweed.[2]
  • Seaweed will improve liver function for faster absorption of medications.[3]
  • Seaweed is high in Potassium, which stabilizes heart rhythm.[4]
  • Potassium in seaweed also improves muscle function, making breathing easier.[4, 5]

2. If you are over 45

  • Improve your diabetes quickly with seaweed. Seaweed improves glucose tolerance.[3]
  • Drop your high blood pressure quickly with seaweed. Clinical trials in both humans and animal models show seaweed reduces hypertension effectively.[2]
  • Seaweed reduces inflammation in the heart, liver, and pancreas, freeing up immune cells for fighting infections. [3]

3. For everyone 

  • Boost immunity. Seaweed is full of minerals, vitamins and antioxidants from seaweed.[6]
  • Seaweed will improve liver function for better blood filtration and nutrient availability.[3]
  • Increase energy levels and general health from better thyroid function with healthy iodine and tyrosine in seaweed.[7]
  • Improve gut health and gut immunity with the prebiotic effects of seaweed.[3]Some cases of the recent pandemic have also caused gastrointestinal problems.
  • Prepare your gut. By eating seaweed, you will boost immunity with seaweed. Who knows?

OVER 60? ONE IN 10 DYING RISK

boost immunity with seaweed

NOT WELL – TIME FOR SEAWEED

Boost Immunity naturally with Seaweed Pacific Seamoss with antiviral properties

Prepare your home

1 Emergency Plan

  • Make sure you have an emergency plan in place.
  • Know what to do BEFORE the need arises.
  • Check out The Red Cross Website can help but also check your Local Government and State Health Departments for more information.

2 Medications

  • Make sure you have 14 days of medications available for you, your family, and pets.
  • You may need to be in-home quarantine for that long.

3 Food and Household Supplies

  • Gradually build up supplies of canned and frozen goods
  • High use items such as toilet paper, tissues.

Further Reading

[1]         WorldoMeters  Last updated: February 23, 2020.

[2] Z. Eshak, “PROTECTIVE EFFECT OF Kappaphycus alvarezii ON THE HEART OF HYPERTENSIVE AND HYPERCHOLESTEROLEMIC INDUCED SPRAGUE-DAWLEY RATS,” Malaysian Journal of Microscopy, vol. 12, no. 1, 2016.

[3] S. Wanyonyi, R. Du Preez, L. Brown, N. A. Paul, and S. K. Panchal, “Kappaphycus alvarezii as a food supplement prevents diet-induced metabolic syndrome in rats,” Nutrients, vol. 9, no. 11, p. 1261, 2017. (Pubmed)

[4] M. S. Stone, L. Martyn, and C. M. Weaver, “Potassium intake, bioavailability, hypertension, and glucose control,” Nutrients, vol. 8, no. 7, p. 444, 2016.

[5] K. S. Kumar, K. Ganesan, K. Selvaraj, and P. S. Rao, “Studies on the functional properties of protein concentrate of Kappaphycus alvarezii (Doty) Doty–An edible seaweed,” Food chemistry, vol. 153, pp. 353-360, 2014.

[6] K. S. Kumar, K. Ganesan, and P. S. Rao, “Antioxidant potential of solvent extracts of Kappaphycus alvarezii (Doty) Doty–An edible seaweed,” Food chemistry, vol. 107, no. 1, pp. 289-295, 2008.

[7] P. Watson, “Tyrosine Supplementation: Can This Amino Acid Boost Brain Dopamine and Improve Physical and Mental Performance?,” Sports Sci. Exch, vol. 28, no. 157, pp. 1-6, 2016.

Categories
Biosea Health Heart Health Reviews

Blood Pressure Control with Seaweed

Blood Pressure Control with Seaweed Dietary Supplement

Hi, I’m Dr Hugh Butler Co-founder.  Over the past 8 years my blood pressure had slowly risen by 15 mmHg  from 120 to 135. I had not realised this until I dug out the data. Was it just that I had aged 8 years? It was not a lifestyle disease as I have been doing upper body exercises and trying to do the moving more. I started eating Pacific Seamoss seaweed in October. The research for blood pressure control with seaweed dietary supplement was in the science literature when we started down this road. To my surprise, my blood pressure fell 15mm over 3 weeks. While 15mm may not seem much, it moves me from a Hazard Ratio from 1 down to 0.8. That’s a risk reduction of a heart event by 30%. (The hazard ratio is logarithmic).[1]

Blood pressure control with seaweed dietary supplement shows rapid decrease in both systolic and diastolic blood pressure
Blood pressure for Hugh Butler from 2013 to 2020, showing slight rise over 7 years due to aging. Seaweed introduced in late October 2019 and rapid decrease in systolic blood pressure.
Blood pressure control is very important for reduction of risks
Hazard ratio of cardiac event. Note the increase from 120 to 140mmHg increases the Hazard ratio by nearly 15%

Blood Pressure Control with Seaweed 2007

Associate Professor Jane Teas [2] published 13 years ago blood pressure could be reduced if people took a seaweed dietary supplement. She published this information in a number of journals and articles but to our surprise, no one seemed to take any notice.

Method

  • She used a good trial design of a double blind crossover clinical trial using 2 groups. One had lower levels of seaweed, with a placebo group and 4g, and another group ate medium (4g) or higher rate of seaweed (6g).
  • The brown seaweed Undaria pinnatifida (Japanese wakame) was the seaweed supplement given.
  • Only the sporophylls of the seaweed were used. This area of seaweed is used for smoothies.
  • The blades and leaves were not used to avoid giving the patients high levels of iodine at the rates used..
  • The seaweed was provided in capsules and treatments were placebo, none, 4g or 6g per day. On the high rate patients needed 12 capsules!

The patients, all volunteers had at least one of the symptoms of metabolic syndrome. The criteria for metabolic syndrome includes at least three of the following four conditions

  • Waist circumference greater than 102 cm for men or greater than 88 cm for women;
  • Fasting triglycerides greater than ≥ 150 mg/dL, HDL cholesterol < 40 mg/dL (male), < 50 mg/dL (female);
  • Blood pressure greater than 130/85 mm Hg;
  • Fasting glucose greater than 110 mg/dL.
wakame parts
The brown seaweed Undaria pinnatifida (Japanese wakame) was harvested, and only the sporophyll part used as the leaf has too much iodine

All the participants had a large waist and 2 of the other symptoms. None of the participants were taking medication.

SEAWEED REDUCED BLOOD PRESSURE AND DECREASED WAIST

blood pressure control with seaweed dietary supplements after 8 weeks of eating seaweed
From Jane Teas 2007. After 8 weeks of consuming seaweed, blood pressure was reduced 14 mmHg, and waist was reduced 6 cm for females in the study.

Results

The results are really clear and blood pressure control with seaweed dietary supplement is unequivocal. Seaweed reduced both blood pressure and weight:

  • Seaweed reduced blood pressure by a about 12 to 16mmHg.
  • There was a dose response. More seaweed reduced blood pressure more.
  • There was no effect when the blood pressure was normal.
  • Some participants (females only) lost over 6 cm of waist and lost weight as well(statistical)

As the trial was restricted to just 8 weeks then some changes may require longer consumption of the seaweed. Pressure Control with Seaweed

Prof Lindsay Brown (Wanyonyi et al 2017 [3]) from the University of Southern Queensland (USQ) has been studying functional foods for over 15 years.  Functional foods are foods that are eaten in normal daily quantity that are just food, but they have a drug like additional effect.  The experiment on blood pressure control with seaweed dietary supplement with Kappaphycus alvarezii was done as a prevention trial.

ANIMALS 2017 – BLOOD PRESSURE CONTROL WITH SEAWEED

Prof Lindsay Brown (Wanyonyi et al 2017 [3]) from the University of Southern Queensland (USQ) has been studying functional foods for over 15 years.  Functional foods are foods that are eaten in normal daily quantity that are just food, but they have a drug like additional effect.  The experiment on blood pressure control with seaweed dietary supplement with Kappaphycus alvarezii was done as a prevention trial.

blood pressure control with seaweed dietary supplement also stopped weight gain
From Wanyonyi 2017. Addition of seaweed prevented weight gain in rats on a junk food diet.
blood pressure control with dietary seaweed supplement in 2017
From Wanyonyi 2017. Seaweed brought down the blood pressure to the same as the standard food diet. Junk food caused hypertension in the animals

Design of Experiment of Dietary Supplement

  • One group of rats were fed normal rat chow.
  • Second group were given a high fat, high sucrose diet (just like junk food)
  • A third group had the junk food along with the seaweed at 5% w/w added to the seaweed.  This amount of seaweed was designed to equate to the amount of seaweed humans are thought to consume daily.

Human: Queen Garnet Plum Trials

Prof Lindsay Brown has published over 174 articles over the past 15 years on “functional foods” and used rat obesity models. For most of these studies, blood pressure was reduced. In work with Queen Garnet Plums, rats showed a remarkable reduction in blood pressure. The animal study was followed by a human study in 2016 with 24 participants showed reduction in blood pressure but no cognitive improvement. [5]. It would not be unreasonable to assume other functional foods all provide reduction in hypertension in humans.

Conclusion: Results Are Hard to Believe!

The logical conclusion is actually very hard to accept.  One can eat junk food with impunity!  Remember, this study is with rats not humans. But the thought that one can eat junk food and instead of becoming obese, its as though you ate a standard diet.

In this animal trial, seaweed protected against

  • Weight gain
  • Increased blood pressure
  • Reduced fatty liver
  • Decreased glucose response
  • Improved inflammatory diseases.
  • Changes in microbiome.

Check out the publication for some of the big changes in inflammation in the heart and stomach.

Why?

The gut microbiome changed markedly. The figure below shows the very large effects on just 4 genera of bacteria. With Bacteriodes, you can see that the junk food diet reduced numbers. Seaweed reversed that and numbers are even higher than the standard diet. With a negative genera such as Clostridiacea bacteria, the levels with the junk food were 3 times higher, and the seaweed reduced the levels right back down to the standard diet.

blood glucose control with seaweed dietary supplement
From Wanyonyi 2017. Blood glucose controlled with seaweed provided as a dietary supplement.
gut microbiome changes are the likely reason that blood pressure control with seaweed dietary supplments worked.
Figure from Waynonyi 2017. The microbiome was radically changed with the introduction of Kappaphycus alvarezii to the diets of the junk food animals.

Animal Studies 2020 – Seaweed

Professor Lindsay Brown and his team from USQ (du Preez et al 2020 [4]) repeated this experiment in 2019.  Professor Nicholas Paul from University of the Sunshine Coast grew the seaweed in tanks at Bribie Island.  The experiment is a repeat of many of Professor Brown’s trials with functional food, in that this trial design is an intervention trial.  An intervention trial feeds rats over 6 to 8 weeks with a junk food diet.  At this stage the rats are obese and have symptoms just like 65% of Australians or 80% of Americans have.  (Like the human patients in Professor Teas trial as above. I.e. hypertension, visceral fat, glucose intolerance etc)

  • They used a Southern Queensland red seaweed called Sarconema filiforme.
  • Trial design was an intervention trial.
  • Rats are fed either a standard or a high fat/sugar diet for 8 weeks. The junk diet has induced obesity in the rats.
  • Treatment was then the introduction of red seaweed at 5% w/w for both standard and junk diets
  • Animals were then measured over the next 8 weeks.
Blood pressure control with seaweed dietary supplement also stopped weight gain
From du Preez 2020 Seaweed reduces weight gain from rats on a junk food diet and makes no different to rats on a standard diet.
Blood pressure control with seaweed dietary supplement reduces liver inflammatory cells
From du Preez 2020. Seaweed markedly reduces liver inflammatory cells in less than 8 weeks. The damage is completely mitigated by the seaweed.

Conclusive Results: Blood Pressure Control with Seaweed

Key findings are much the same as in their previous seaweed prevention trial, the multiple trials with other functional food or even Professor Teas trials from 15 years previously.

  • Seaweed started to reverse the weight gain from junk food.
  • Seaweed decreased abdominal and liver fat.
  • Junk food massively increased inflamed fatty liver cells
  • Seaweed completely reversed the number of fatty liver cells by 100%. So while weight may not have returned to normal, inflammation from the junk diet disappeared.
  • Total plasma cholesterol concentrations fell.
  • Blood pressure increase by junk food was completely reversed by eating seaweed.
Blood pressure control with dietary seaweed supplement mmHg
Figure from du Preez et al 2020. Data shows significant reduction. Seaweed reduced blood pressure back to normal
From du Preez 2020. Sarconema seaweed reduced plasma total cholesterol significantly. See publication for other metabolic variables

Microbiome are Key to Understanding

Like the previous 2017 paper gut microbiome changed. The correlation (Figure 12 of du Preez) is shown below.

Furthermore the authors were able to correlate between the bacterial community structure and the physiological parameters.

gut microbiome correlelates with blood pressure control with seaweed dietary supplements
Figure du Preez et al 2020. The correlation between gut microbiome genera and physiological outcomes.

Conclusions – Unbelievable!

If you must eat eat junk food, eat seaweed. Seaweed reduces blood pressure ( hypertension); seaweed eliminates fatty liver; reduces inflammation; eliminates glucose intolerant; reduces high cholesterol, and reduces weight.

References

[1] Wu, C.-Y. et al. High Blood Pressure and All-Cause and Cardiovascular Disease Mortalities in Community-Dwelling Older Adults. Medicine (Baltimore) 94, (2015).

[2] Teas, J. et al. Could dietary seaweed reverse the metabolic syndrome? 145–157 http://apjcn.nhri.org.tw/server/APJCN/18/2/145.pdf (2009).

[3] Wanyonyi, S., du Preez, R., Brown, L., Paul, N. A. & Panchal, S. K. Kappaphycus alvarezii as a Food Supplement Prevents Diet-Induced Metabolic Syndrome in Rats. Nutrients 9, 2 (2017).

[4] du Preez, R. et al. Carrageenans from the Red Seaweed Sarconema filiforme Attenuate Symptoms of Diet-Induced Metabolic Syndrome in Rats. Mar. Drugs 18, 97 (2020).

[5] E.O. Igwe, K.E. Charlton, S. Roodenrys, K. Kent, K. Fanning, M.E. Netzel 2017. Anthocyanin-rich plum juice reduces ambulatory blood pressure but not acute cognitive function in younger and older adults: a pilot crossover dose-timing study. Nutrition Research 47 28-43 https://doi.org/10.1016/j.nutres.2017.08.00

Categories
Biosea Health Heart Health

Healthy Heart on Seaweed

The cardiovascular system is made up of the heart and all the arteries, veins and capillaries that are threaded throughout the body. The number one role is to deliver oxygen to every cell in the body. Get a healthy heart on seaweed. The heart is the strong pump that drives the oxygen delivery and beats from the first weeks after conception through to our last breath. No wonder heart health is so important.

Un-Healthy Heart – Cardiovascular Disease

The term “cardiovascular disease” can refer to a raft of heart and arterial diseases that affect this system. These range from aortic aneurysms to congestive heart failure, coronary artery disease and stroke. All these conditions have the same underlying causes that are either modifiable, like diet, or non- modifiable like genetics. We are all well educated about how to change our lifestyle to prevent heart disease. But despite major medical advances and public health campaigns over the past decades, Cardiovascular Disease remains the number one cause of death for both men and women in Australia. [1]

Health Food –> Healthy Heart

Science tells us that the solution may be easier and more readily available than the medical profession would have us believe. Nations with low rates of cardiovascular diseases, such as Japan, eat a diet rich in seaweed. The evidence is clear that on the Japanese diet of 1975 they had healthy heart on seaweed diet. This sea vegetable is rich in novel phytochemicals that create functional changes in the body when consumed regularly.

How Can Seaweed Help Prevent Cardiovascular Disease?

Healthy Heart on Seaweed as fresh or dried improves heart health1. Seaweed reduces blood pressure.

The mechanism is not known, but several studies have shown that systolic blood pressure is returned to normal range in rats when seaweed is included in the daily diet for several weeks. [2]. One study compared seaweed intake with blood pressure medication and found regular seaweed consumption caused the same BP reduction as an ACE Inhibitor. [3]. The effect has been shown to be just as strong in humans, dropping high blood pressure to normal measures, while not lowering healthy pressure. [4] This suggests the seaweed is returning the cardiovascular system to health, rather than just dropping blood pressure in isolation.

2. Healthy heart on seaweed – prevents ventricular hypertrophy

When the heart muscle is placed under stress because of high blood pressure the body compensates by thickening the walls of the heart. This reduces the size of the chamber into which the blood flows. The heart is unable to effectively pump anymore eventually lead to heart failure. Studies have shown that seaweed prevents the hypertrophic thickening of the heart walls even in the context of a high fat diet. [3]

3. Healthy Heart on Seaweed prevents cardiac fibrosis

In any state of cardiac stress or disease, a structural protein, collagen, builds up in the heart muscle causing fibrosis – a hardening and enlarging of the heart muscle. This limits the ability of the heart muscle to contract and interferes with the electrical conduction that makes your heart beat regularly. Cardiac fibrosis is progressive and eventually leads to heart failure. Seaweed removes collagen from heart tissue independent of dietary and lifestyle changes. [2]

4. Seaweed Reduces Blood Lipids

Caused by a diet high in fat or genetic predisposition, high cholesterol, particularly bad LDL cholesterol, leads to arterial plaques the eventually block arteries, particularly the coronary arteries. These are the small arteries that run along the outside of the heart bringing blood supply and oxygen to the heart muscle itself. When these arteries are blocked the heart muscles stops functioning and may die – this is called myocardial infarction, commonly known as a heart attack. Seaweed has been shown to interfere with the normal mechanisms of lipid breakdown, preventing dietary fats from building up in the blood stream and causing arterial plaques.[2] One study showed seaweed was as effective as a statin medication in reducing cholesterol. [3]

5. Seaweed reduces inflammation

Most cardiac disease is ultimately caused by inflammatory processes in the body. Damage ranges from hardening of small injuries to the arteries caused by arterial plaques, or invasion of inflammatory cells into the heart muscle itself. Seaweed has a dual action to remove inflammation in the heart and the arteries. The prebiotic component of seaweed upregulates good bacteria in the colon which in turns sends anti-inflammatory molecules into the blood stream to reach the arteries and heart.[5] In a second, unknown mechanism, seaweed removes inflammatory cells that build up in the cardiac muscle from stress, western diet or age. [2].  The Japanese demonstrate that you get a healthy heart on seaweed.

Check out a detailed science review on Blood Pressure Control with Seaweed Dietary Supplement

References

[1] A. I. o. Health and Welfare, “Deaths in Australia,” AIHW, Canberra2019, Available: https://www.aihw.gov.au/reports/life-expectancy-death/deaths-in-australia.

[2] S. Wanyonyi, R. Du Preez, L. Brown, N. A. Paul, and S. K. Panchal, “Kappaphycus alvarezii as a food supplement prevents diet-induced metabolic syndrome in rats,” Nutrients, vol. 9, no. 11, p. 1261, 2017.

[3] Z. Eshak, “PROTECTIVE EFFECT OF Kappaphycus alvarezii ON THE HEART OF HYPERTENSIVE AND HYPERCHOLESTEROLEMIC INDUCED SPRAGUE-DAWLEY RATS,” Malaysian Journal of Microscopy, vol. 12, no. 1, 2016.

[4] J. Teas, M. E. Baldeón, D. E. Chiriboga, J. R. Davis, A. J. Sarriés, and L. E. Braverman, “Could dietary seaweed reverse the metabolic syndrome?,” Asia Pacific journal of clinical nutrition, vol. 18, no. 2, p. 145, 2009.

[5] I. Sekirov, S. L. Russell, L. C. M. Antunes, and B. B. Finlay, “Gut microbiota in health and disease,” Physiological reviews, vol. 90, no. 3, pp. 859-904, 2010.

Categories
Biosea Health Heart Health

Nothing says I love you more than seaweed

The fairy tale has come true. You have found that special someone who will be beside you for the rest of your life. You are living the happily ever after.
Building a life together, raising a family, weathering life’s storms all make the bonds of love grow deeper and stronger. But as we age, we see other couples who have lost partners early because of cancer or heart disease. And we realize the fragility of life and the importance of your own relationship and the health of your partner.

Valentines Day Gift

This Valentine’s Day give your loved one the gift of health and longevity with seaweed.
Japan, particularly the island of Okinawa, is known for its high numbers of people living healthily well into their 90s and beyond. A daily intake of seaweed is one of the main reasons why health outcomes are so good in the Okinawan population. Sadly, studies have shown that switching the traditional seaweed-based diet to the typical western diet reverses all the positive effects and disease revert to the same as those in western countries.

Nothing says I love you more with Seaweed. Why?

Seaweed has a strong impact on health.

1. Seaweed is a potent prebiotic

Seaweed feeds the healthy bacteria in the gut. Healthy gut bacteria produce bioactive metabolites that cross into the blood stream for delivery to all the cells in the body. These metabolites have wide ranging effects including reducing inflammation, improving liver and heart function, and improving immunity. If you give seaweed, improving gut health. Nothing says I love you more than seaweed!

2. Seaweed Novel Compounts

Seaweed is full of novel compounds not found in terrestrial plants. These compounds, such as sulphated galactans, have powerful effects on cellular processes. These drive the immune and healing mechanisms in the body to produce anti-cancer, anti-inflammatory and anti-diabetic properties.

3. Seaweed high in potassium

Potassium is essential for a healthy heart. It also relaxes the muscles built into arterial wall, reducing blood pressure. This makes the heart less burdened, but it also protects the very small blood vessels in the brain, important for dementia prevention.

Seaweed is the gift for a lifetime.

Seaweed – the smart organic medicinal food for boosting your immunity

Categories
Alzheimer's Disease Arthritis Biosea Health Heart Health Weight loss

8 Signs You Need Seaweed in Your Life

Seaweed is a functional food that has prebiotic properties along with novel bioactive compounds. Because of this, seaweed has a wide range of medicinal like properties that counteract the ailments and disease of the modern lifestyle. Eight signs you need seaweed in your life.

1. Panda Eyes

Are you sleeping well but still have dark rings around your eyes? Its probably due to a sluggish liver. Eating a typical western diet can cause a buildup of fatty lobules in the liver, slowing down the important functions of filtration. Toxins increase in the blood stream and we notice this around the eyes. Research from the University of Southern Queensland shows that taking seaweed every day effectively reverses the negative effects of our western diet and removes the fat from our livers. As an added bonus, liver enzymes tests showed a return to optimal functioning even when an unhealthy diet was being consumed. [1]

2. Waistline expanding

We all seem to be in a constant battle with the bulge, especially as we get a little older. Studies have shown that daily intake of seaweed changes the way fats are processed by the body. Seaweed flicks the switch to make the body use fat for energy. It also prevents new fat cells from being created every time we eat just that little bit too much. This all adds up to a drop in waist circumference of up to several centimeters. [1-3]

3. Feeling more tired than usual

Fatigue is a modern-day epidemic that undermines the enjoyment of life at best, but at worst can lead to accidents. Seaweed is a functional food that is rich in bioactive compounds to counter fatigue, no matter the cause. Fatigue from an underperforming thyroid is alleviated by the building blocks of thyroid hormone, iodine and tyrosine found in natural balance in seaweed. Tyrosine is also needed to produce neurotransmitters dopamine and noradrenaline which allow our brains to function better when under stress. [4]

4. Harder to remember things- Seaweed in your life

Most of us see memory problems are inevitable as we get older, but this is not necessarily the case. A team of scientists from Korea have shown that seaweed can repair neurons on the brain and increase neural networks that are necessary for memory. That study also found that neurons were able to better manufacture and store the neurotransmitters necessary for faster mental processing. [5]

5. Aching Joints – Seaweed in your life

Inflammation in the joints can happen at any age, with causes ranging from mild injury to overuse or arthritis. For centuries seaweed has been used in traditional medicine as an anti-inflammatory but now modern science is demonstrating just how effective it is. One study described the compounds from seaweed as having a greater anti-inflammatory capacity than aspirin. [6] The benefit of seaweed is that it doesn’t have the side-effects seen in many anti-inflammatory drugs, such as damage to the stomach lining. Check out the surprising testimonies.

6. Blood pressure creeping up

Hypertension is another “lifestyle” disease that has a myriad of causes – western diet, stress, lack of exercise, age or genetics. It is a leading “modifiable risk-factor” factor that increases the probability of death from heart attack, stroke or heart failure. Anyone who has been diagnosed with hypertension knows how difficult it is to lower your blood pressure, even when medicated. The good news is taking seaweed every day has been shown to reduce systolic ( the first number) blood pressure back to normal values. [1] Check your blood pressure

7. Painful periods

Contractions of the uterus can create sever and debilitating pain. Many women suffer from pain so great they are unable to work or function normally during a menstrual period. Seaweed has a high level of natural potassium that reduces smooth muscle contractions and restores the sodium potassium balance in the body. While the uterus still contracts during menstruation, it is far less extreme so pain is significantly reduced. [1]

8. You’re over 50 – you need seaweed in your life

Fifty seems to be the magic number when lifestyle and genetics start to catch up with us. Cardiovascular disease, cancer, and diabetes suddenly loom large in our lives, and in the minds of our general practitioners. Countries that have a high consumption of seaweed, like Japan, have a decreased risk of all these major diseases.[7] This is probably why these same countries have so many healthy, active people in the 80s, 90s and 100s. Interestingly, studies have shown that when these people change to a western diet their biological markers, like blood pressure, shift to a level similar to those raised in the western world. [7]

References

[1] S. Wanyonyi, R. Du Preez, L. Brown, N. A. Paul, and S. K. Panchal, “Kappaphycus alvarezii as a food supplement prevents diet-induced metabolic syndrome in rats,” Nutrients, vol. 9, no. 11, p. 1261, 2017. (Pubmed)

[2] J. Teas, M. E. Baldeón, D. E. Chiriboga, J. R. Davis, A. J. Sarriés, and L. E. Braverman, “Could dietary seaweed reverse the metabolic syndrome?,” Asia Pacific journal of clinical nutrition, vol. 18, no. 2, p. 145, 2009.(Pubmed)

[3] Y. X. Chin, Y. Mi, W. X. Cao, P. E. Lim, C. H. Xue, and Q. J. Tang, “A pilot study on anti-obesity mechanisms of Kappaphycus alvarezii: The role of native κ-carrageenan and the leftover sans-carrageenan fraction,” Nutrients, vol. 11, no. 5, p. 1133, 2019.

[4] M. L. Cornish, A. T. Critchley, and O. G. Mouritsen, “Consumption of seaweeds and the human brain,” Journal of Applied Phycology, vol. 29, no. 5, pp. 2377-2398, 2017.

[5] G. Tirtawijaya et al., “Spinogenesis and Synaptogenesis Effects of the Red Seaweed Kappaphycus alvarezii and Its Isolated Cholesterol on Hippocampal Neuron Cultures,” Preventive Nutrition and Food Science, vol. 24, no. 4, p. 418, 2019.

[6] F. Makkar and K. Chakraborty, “Antidiabetic and anti-inflammatory potential of sulphated polygalactans from red seaweeds Kappaphycus alvarezii and Gracilaria opuntia,” International Journal of Food Properties, vol. 20, no. 6, pp. 1326-1337, 2017.

[7] E. M. Brown et al., “Seaweed and human health,” Nutrition reviews, vol. 72, no. 3, pp. 205-216, 2014.

Categories
Arthritis Biosea Health Heart Health

Seaweed Helps Exercise and Breaks Down Barriers

Doctors continually recommend lifestyle changes – eat better, exercise more. But did you know that seaweed helps exercise?  Doctors know exercise reduces or reverses major diseases of the modern age – the big five Cardiovascular Disease, Diabetes, Depression, Obesity and Cancer.

But if exercise was that simple, we would all be doing it. There are many physical barriers to why we resist taking a long walk or a trip to the gym. We often tell ourselves, and our friends, that it’s because we don’t have the time or the money. But it’s usually more to do with how we feel about exercise, and our general health and energy levels.

Our first buyers tell us seaweed helps exercise and breaks barriers. Seaweed changes the way people feel about exercise. Here are some of the reasons why.

1. Seaweed Helps Exercise & provides extra energy

Seaweed cleans out your sluggish liver, so nutrients and energy are quickly delivered to cells and muscles when they are needed. We experience this as a feeling of sustained energy and wellness. Customers describe it as feeling youthful with energy to burn. Moving is easy and the element of fun re-emerges, instead of the drudgery we often associate with physical activity.

2 Seaweed Helps Exercise as it reduces joint inflammation

It’s difficult to move more when movement causes pain and swelling. Seaweed reduces joint inflammation in two ways. Firstly, it provides a rich supplement of prebiotics that boost good bacteria in the gut that in turn send natural anti- inflammatory molecules throughout the body. Secondly, it contains natural pharmaceutical molecules that interfere with the chronic inflammatory processes, stopping long term inflammation in its tracks.

3. Seaweed changes brain chemistry

One of the modern diseases is depression. While we don’t all have major depression, it is easy to suffer from the symptoms of depression including lethargy, feeling low, lacking motivation. It’s simple combination of the western diet, lifestyle and the heavy burden of stress we all carry. Seaweed makes us feel better about life in two ways. It provides taurine, tyrosine and other essential compounds that act on neural pathways to reduce anxiety and tension during periods of stress. Then the prebiotic elements of seaweed upregulate good bacteria in the gut. This reduces inflammation in the brain creating a feeling of wellbeing and halting negative thinking patterns.

4. Seaweed helps exercise as it makes your heart work better

Studies have shown seaweed removes the build-up of structural compounds, like collagen, from heart tissues. This allows cardiac muscle to move more freely, delivering oxygen to muscles when you need it most, such as when you are exercising. Suddenly that hill climb is easier because muscles are receiving the blood flow they need to work harder.

Categories
Arthritis Biosea Health Gut Microbiome Heart Health Weight loss

5 Reasons to Feel Better with Seaweed

Adding seaweed to our diet provides 5 reasons to feel better with seaweed. Our customers tell us they have more energy and enthusiasm for life. There is no question that adding seaweed to our diet makes us feel better. There is sound scientific reason for the health and wellbeing improvements that happen when you take seaweed every day. Here are just 5 reasons to feel better with seaweed and their main benefits according to published peer-reviewed science.

1 of 5 Reasons to feel  better with Seaweed is your Liver is Cleansed

The liver is a manufacturing and storage plant for all the nutrients, enzymes and proteins our body uses every day. It is also the major filtration system for removal of toxins and metabolic wastes. Unfortunately, the western diet causes the liver to become clogged with lobules of fat and then inflammation sets in. This interferes with the liver’s ability to do its job. Toxins begin to build up and vital molecules fail to reach the cells where they are needed. Seaweed removes the fatty build and halts the inflammatory response, so the liver begins to function properly again. [1].  In Professor Brown’s work, the inflammation of the liver is the first sign they see in their rats on a seaweed diet.

2. Inflammation is reduced

Inflammation is a cascade of biochemical and cellular responses designed to protect the body in case of injury or infection. Our modern lifestyle and diet mean we face infectious agents, pollutants and minor injury daily. When you add stress into the mix the process of inflammation becomes chronic leading to disease in the body. Seaweed reduces inflammation in two major ways. Sulphated polygalactan in seaweed works like aspirin to stop the inflammation process [2]. The prebiotic activity of seaweed promotes good gut bacteria that release a variety of anti-inflammatory molecules into the body[3]. So out joints are more free and overall inflammation is reduced. Reduced inflammation also means less energy is diverted to the immune system. Hence, we feel less tired.

3. Thyroid Function is Better

Iodine and tyrosine are the key molecules needed to produce thyroid hormones. Thyroid hormones control metabolism at the cellular level and are necessary for proper functioning of all systems in the body. When iodine and tyrosine are in short supply thyroid hormones aren’t produced and metabolism is sluggish. This is experienced as weight gain, lack of energy and feeling cold all the time. Seaweed has healthy levels of bioavailable iodine and tyrosine for optimal hormone production and thyroid function.

4 of 5 Reasons to feel better with Seaweed is Sodium Potassium Balance Improvement

Sodium and potassium are related elements that are vital to life. The western diet tends to be high in sodium but low in potassium, so over 98% of American adults are potassium deficient. Signs of low potassium include fatigue, muscle weakness or cramps and constipation. Diets low in potassium are also known to cause hypertension. Seaweed is high in potassium but low in sodium (4 to 1 ratio) thus can correct the sodium potassium balance. When balanced, potassium makes muscle contraction easier, including the muscles in the arteries, so less effort is required, and fatigue is reduced.

5 of 5 Reasons to Feel Better with Seaweed: Brain function improvement

Seaweed contains many different neurotrophic factors that increase neural connections and generate new cells in the brain. Plant sterols in seaweed create an enriched environment for increased cell connections resulting in improved memory and quicker cognition. [4] Seaweed is also rich in the ancient molecule taurine that helps generate new brain cells. [5] Tyrosine increases dopamine and noradrenaline in the brain, creating feelings of motivation, reward and decreased fatigue, and this has been linked to enhanced performance.[6]

References

[1] S. Wanyonyi, R. Du Preez, L. Brown, N. A. Paul, and S. K. Panchal, “Kappaphycus alvarezii as a food supplement prevents diet-induced metabolic syndrome in rats,” Nutrients, vol. 9, no. 11, p. 1261, 2017. (Open Access)

[2] F. Makkar and K. Chakraborty, “Antidiabetic and anti-inflammatory potential of sulphated polygalactans from red seaweeds Kappaphycus alvarezii and Gracilaria opuntia,” International Journal of Food Properties, vol. 20, no. 6, pp. 1326-1337, 2017. (Food Online)

[3] I. Sekirov, S. L. Russell, L. C. M. Antunes, and B. B. Finlay, “Gut microbiota in health and disease,” Physiological reviews, vol. 90, no. 3, pp. 859-904, 2010.

[4] G. Tirtawijaya et al., “Spinogenesis and Synaptogenesis Effects of the Red Seaweed Kappaphycus alvarezii and Its Isolated Cholesterol on Hippocampal Neuron Cultures,” Preventive Nutrition and Food Science, vol. 24, no. 4, p. 418, 2019. (pubmed)

[5] M. L. Cornish, A. T. Critchley, and O. G. Mouritsen, “Consumption of seaweeds and the human brain,” Journal of Applied Phycology, vol. 29, no. 5, pp. 2377-2398, 2017. (SpringerLink)

[6] P. Watson, “Tyrosine Supplementation: Can This Amino Acid Boost Brain Dopamine and Improve Physical and Mental Performance?,” Sports Sci. Exch, vol. 28, no. 157, pp. 1-6, 2016. Reference

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Arthritis Biosea Health Health Benefits Heart Health

Six Health Improvements People Are Saying About Pacific Seamoss

Six health improvements are what customers are saying. After consuming Pacific Seamoss for 4 to 12 weeks, what’s their stories? We share below some of the stories. Check out testimonials here.

The good thing about a functional food like Pacific Seamoss, is that it has different effects for different people. Functional foods are so packed with nutrition and natural pharmaceuticals, that they provide the right supplement that your body needs, whether you knew it or not. That said, there seem to be some effects that all our customers are telling us about. Here are the top 6 changes that our Pacific Seamoss customers report.

1. More energy

All our customers reported they were feeling more energetic and able to cope better with the demands of their busy lives. Those that are regular exercisers have found exercise easier. Those that were mostly sedentary tell us they are feeling more energetic and are moving a lot more. The functional foods expert, Professor Lindsay Brown from the University of Southern Queensland, tells us this is because of dramatic changes in the liver allowing faster delivery of nutrients and energy to our cells and muscles.[2,3]

2. General feeling of wellness.

Many of our older customers say they feel better than they have felt for many years. This is not just about more energy but a feeling a positive mindset and am overall sense of wellbeing. All our customers have told us that they are feeling more relaxed, able to cope better with stress and feel less emotionally drained from everyday worries. Pacific Seamoss is packed full of tyrosine, that improves mental alertness and focus during times of stress, giving us a sense of control and reducing anxiety and tension.

3. Reduced Blood pressure

High blood pressure (hypertension) is a silent killer that is much too easy to develop but very difficult to reduce. Many of our customers take regular prescription medications for hypertension. They tell us that even though medicated, their blood pressure continues to creep up. Inevitably the dosage is increased but so are the nasty side effects. But now, our customers have reported that medications had to be reduced because blood pressures are returning to the normal range. Their doctors are pleased because heart health is improving, and risk of major cardiovascular disease is reduced. Our scientists say it’s probably the Potassium in the Pacific Seamoss that helps regulate the Potassium/Sodium balance in the body and is especially important for heart health.

4. Reduced Joint inflammation

Inflammation in joints occurs for many reasons, the two most common being overuse and arthritis. Both conditions interfere with normal function and stop us from leading a healthy active life. With Pacific Seamoss our customers are reporting pain and inflammation is reduced in arthritic or injured joints. They say they are active again, and greatly appreciate the better quality of life. Even our more athletic customers tell us their niggling training injuries have disappeared. Pacific Seamoss contains plant sterols and other macronutrients that interfere with the chronic inflammation process. It also acts as a pre-biotic – up-regulating your healthy gut bacteria that pump inflammation reducing short chain fatty acids into the blood stream.

5. Minds are much sharper

This is one feature of Pacific Seamoss that we didn’t expect. Many of our customers are reporting sharper minds and easier memory recall. This is especially good news for our older customers, who report age related memory issues are much improved. A new study from scientists in Korea shows that Pacific Seamoss provides neurotrophic factors, otherwise known as s nutrition for brain cells. The seaweed helps to regenerate and repair ageing and damaged cells, while also increasing the availability of neurotransmitters that build strong healthy networks and increase brain plasticity. This is great news for anyone with a history of neurodegenerative conditions, including Parkinson’s Disease, Alzheimer’s and Stroke. It’s also great news for those of us trying to prevent the cognitive decline that occurs when we age.

6. Even More

The best part about keeping in touch with our customers us that we get feedback about changes in health and wellbeing that we previously hadn’t studied. This gives us an opportunity to explore the scientific literature and develop new studies to further expand the scientific knowledge about Pacific Seamoss. That’s what good science is all about. Here are some of the anecdotal reports we are currently looking at.

  • Dysmenorrhoea Painful periods are dramatically reduced in long term sufferers. Likely mechanism – oestrogen management, Potassium/Sodium Balance
  • Hair and Nail Growth Increased growth rate of hair and nails. Likely mechanism – liver up-regulation,
  • Healthy Glowing Skin – Skin conditions improved, and signs of ageing reduced. Likely mechanism – collagen released from inflamed organs made available for skin health, improved microbiome.
  • Relief for Parkinson’s Symptoms – Customers with early-stage Parkinson’s disease have reported easier movement. Likely mechanism – tyrosine in Pacific Seamoss is converted to L-Dopa in the body, improved liver function allowing better delivery to the cells.
  • Improved gut and bowel movements.

What has been your experience with Pacific Seamoss? Do you have six health improvements?

Let us know at seaweed@bioseahealth.com

References

[1] Tirtawijaya, G., Haque, M. N., Choi, J. S., Moon, I. S., Meinita, M. D. N., Choi, J.-S., & Hong, Y.-K. (2019). Spinogenesis and Synaptogenesis Effects of the Red Seaweed Kappaphycus alvarezii and Its Isolated Cholesterol on Hippocampal Neuron Cultures. Preventive Nutrition and Food Science, 24(4), 418. (PubMed)

[2] Wanyonyi, S., Du Preez, R., Brown, L., Paul, N. A., & Panchal, S. K. (2017). Kappaphycus alvarezii as a food supplement prevents diet-induced metabolic syndrome in rats. Nutrients, 9(11), 1261.(Pubmed)

[3] du Preez, R.; Paul, N.; Mouatt, P.; Majzoub, M.E.; Thomas, T.; Panchal, S.K.; Brown, L. Carrageenans from the Red Seaweed Sarconema filiforme Attenuate Symptoms of Diet-Induced Metabolic Syndrome in Rats. Mar. Drugs 202018, 97.

Categories
Biosea Health Gut Microbiome Heart Health Seaweed for Humanity

Experience backed by Science

Is consumer experience backed by science?  What we are looking for is that science provides validation for personal experiences. Seaweed improves health. Scientists know why your blood pressure improves by 15mm Hg. Long term science backs up personal  health improvement. However, one cannot make any health claim. Because the regulatory industry was established for artificial drugs and medicines, and functional foods struggle for registration and have to be tested in human and animal clinical trials.

There are some clinical trials on humans. There are thousands of peer reviewed publications on the health improvements in vitro, in animals and for limited studies, humans. Google Search for “seaweed functional food” returns 3.5 million hits.

Is Experience Backed By Science?

Discussion and peer reviewed publications with

  • Professor Lindsay Brown University of Southern Queensland (been doing research for 20 years on superfoods)
  • Professor Jane Teas Southern Carolina University
  • Dr Jan Villasend – Aarhus University Hospital in clinical research arthritis in Denmark
  • Dr Monique Mulder Erasmus University Medical Center Rotterdam, The Netherlands.

Our “Pacific Seamoss” red seaweed is 35% sulfated polysaccharide and is pretty indigestible, and passes through the stomach into the intestines. The microbiome get busy on it and composition changes and protects the lining. As well as the extra fibre, and normalisation of the bacteria, some of the other 1000 compounds in the seaweed get absorbed. Some of the compounds have been identified and implicated in the beneficial effects. (eg fucoidan) but there are many unknowns on the mechanism.

Some brown seaweeds (Kelp, Dulce) have an issue with iodine levels too high so you cannot eat the 5+ grams per day of seaweed. The five grams is a daily serve of veges.
Is there a major difference between seaweeds. Possibly if you refine them. But if you have them whole there may not be due to the very complicated interactions.

Metabolic Syndrome Clinical Trial with Humans – 2013

Prof Jane Teas. Did a human double blind clinical trial on 40 overweight volunteers who were already on blood pressure tablets and statins. They all had metabolic syndrome so they all had 2 of those symptoms – Hypertension, weight, high cholesterol and sugar intolerance. They were given 5gm of seaweed, between 4 and 8 gm depending on the treatments.

Significant Outcome. Blood pressure was down 10mm Hg. Patients lost on average 3 kg. There was a reduction in type 2 diabetes. Their cholesterol went down by 2 whole points.  The attached paper has more details.

Animal Studies Obesity Fats Rats made Thin 2017

Professor Lindsay Brown from University of Southern Queensland / UQ has been doing functional food research for 15 years on animals. They did do some human trials on Queen Garnet Plums through Univ Victoria with Nutrafruit.com.au. Over his research spanning 2 decades and multiple products, including purple fruits (with anthrocyanin), purple carrots, purple plums, purple corn and also on linseed, and more recently on seaweed with various species the results are the same.

  • Improvement of gut microbiome
  • Reduction or elimination of fatty liver
  • Bone density increase
  • Blood pressure reduction
  • Weight loss reduction
  • Cartilage increase .

What is interesting that essentially fatty liver disease is gone, heart fibrous tissue gone, cholesterol down and good DNA data from the gut microbiome returning to normal.

Prof Brown’s conclusion is that there is no real difference between the whole food and if you try to split out the active compounds. They had done the work for the purple plum and the outcomes were the same for the whole food versus the identified other compounds.

Some of his work has been documented in the media.

Diabetes

Prof Brown’s work with rats over the past 15 years shows all of these conditions improve with the super food. Be it purple carrots, linseed, Purple Garnet Plums, Purple Corn, Achacha (Garcinia humalis) Mangostem, Seaweed. As consumers start to eat seaweed daily then it is clear that consumer experience backed by science, and the challenge is to undertake more science on humans that continue to do work on animal studies.

Fatty Liver and Kidney Disease

In the animal studies Lindsay showed reversal of metabolic syndrome and that fatty liver disappear and kidney function returns.

Breast Cancer – Humans 2013

A short single blind trial by Jane Teas in 2013. Only 16 people, all breast cancer survivors and only for 12 weeks. 4 weeks placebo, 4 weeks 5 gm Unadaria (a brown). The Creatinine levels halved. Creatinine is a marker of inflammation and more importantly implicated in breast cancer. . She was looking to explain why Japanese women have 1/10 breast cancer rates of those in USA

“uPAR is higher among postmenopausal women generally, and for BC patients, it is associated with unfavorable BC prognosis. By lowering uPAR, dietary seaweed may help explain lower BC incidence and mortality among postmenopausal women in Japan. “

There is other animal and invitro studies and it shows that in mice the oestrogen was stripped out. See this blog

Dementia 2019

Prof Brown says animal studies in dementia do not translate well into humans and that 1 drug out of 200 is the track record to date. But Dr Monique Mulder with Sargassum (brown) and others published in Nature in March 2019 that Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model. The thing seems to be multi-modal in that it provides plant sterols to the brain crossing the blood brain barrier, and stops amyloid plaques and tangles. And reverses it in mice. They are moving from animals to humans in their trials.

Rheumatoid Arthritis and Bowel Inflammation

Dr Jan Villadsen got given some seaweed/rapeseed/fermented mix from FermBiotics.com from his University friend Dr Belinda Bjerre who is a Project Diretor on some of the EU seaweed research programs. The mix was to developed to eliminate use of zinc oxide and antibiotics in pig production. The pig studies show equivalence or better than conventional Zn+antibiotic treatments. Note: zinc is banned in EU animal feed from 2022. A long term rheumatic arthritis (RA) sufferer, Dr Villadsen’s C-Reactive Protein goes to zero in 17 days. Patent. Publications. He and colleagues at Aarhaus are now doing a clinical trial with 200 patients on IBS and RA .

Osteo Athritis

We don’t know exactly which of the 100 different types of arthritis seaweed will work on. There is consistent strong anecdotal evidence. There is in vitro studies. A Nature publication from Prof Xiao and Prof Brown [6] demonstrated when they took the rats from Browns metabolic studies and they identified collagen and connective growth recovery in the rats. This is similar to the osteoarthritis work with extracted fucoidan extracts from brown seaweed.

Conclusion

Functional foods can provide health benefits by reducing the risk of chronic diseases and enhancing the ability to manage chronic diseases, and improving the quality of life. This gives seaweed great potential as a supplement in functional food or for the extraction of compounds.

Our company has a challenge to accelerate the clinical trials and register the benefits to be able to make health claims. Pacific Seamoss is just food. But make your own judgement. No one is stopping you eat food. Even nail growth! We have people where their nails grow more and this is a prime experience backed by science over 11 years ago.

References

[1] Wanyonyi, S; du Preez, R; Brown, L; Paul, N; Panchal, S  2017 Kappaphycus alvarezii as a Food Supplement Prevents Diet-Induced Metabolic Syndrome in Rats. Nutrients (9) 11 DOI:10.3390/nu9111261 (Click for Abstract) (Click to download full paper)

[2] Teas, J et al  2009 Could dietary seaweed reverse the metabolic syndrome? Asia Pac J Clin Nutr 18 (2) 145-157 (Click for Abstract) (Click to download full paper)

[3] Teas, J et al 2013 The consumption of seaweed as a protective factor in the etiology of breast cancer: proof of principle. J Appl Phycol 25 771-779  DOI:10.1007/s10811-012-9931-0 (Click for Abstract) (Click to download full paper)

[4] Bogie, J et al (Including Monique Mulder) 2019 Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model. Scientific Reports 9 (1) DOI 10.1038/s41598-019-41399-4 (Click for Abstract) (Click to download full paper)

[5] Villasend J;  Silkeborg R 2019 Clinical trial: Investigation of macroalgae as a synbiotic adjuvant in chronic inflammatory diseases. Seagriculture19 Belgium presentation  (Click to download presentation)

[6] Sekar, S., Shafie, S., Prasadam, I. et al. Saturated fatty acids induce development of both metabolic syndrome and osteoarthritis in rats. Sci Rep 7, 46457 (2017). https://doi.org/10.1038/srep46457

Media

  • https://www.abc.net.au/local/archives/landline/content/2016/s4419411.htm
  • https://www.abc.net.au/local/archives/landline/content/2015/s4180101.htm
  • https://www.abc.net.au/news/2017-07-15/sleeping-giant:-linseeds-health-properties-could/8711970