Rats Fed Seaweed Reverse Metabolic Syndrome

Rats Fed Seaweed Metabolic Syndrome

Rats Fed Seaweed Reverse Metabolic Syndrome

Take rats and feed them a junk food diet. Or give them a junk food diet plus seaweed. The Seaweed negates the effects of the junk food diet. Sounds too good to be true. Professor Brown was astonished. This animal study was published in 2017 but few seem to understand the ramifications.  You can negate a junk food diet with seaweed. Alternatively, you will be able to reverse the ill-health effects of a bad diet.

The Trial

Professor Lindsay Brown University of Southern Queensland supervised this PhD study along with Dr Sunil Pachal at the University of Southern Queensland.  The paper is below.

They took rats and fed some of them on an junk food (extra sugar + fat) diet.  Just like in the movie Super Size Me, a 2004 American documentary film directed by and starring Morgan Spurlock. Spurlock’s film follows a 30-day period from February 1 to March 2, 2003, during which he ate only McDonald’s food. The film documents this lifestyle’s drastic effect on Spurlock’s physical and psychological well-being. If you want to see what a human on junk food diet looks like. Or not.

Professor Brown’s trial had 3 groups of 10 rats each.  Group 1 had normal rat diet. Group 2 had a Junk food diet. Group 3 had the junk food diet plus some seaweed (Kappaphycus sp) .  The trial went for 8 weeks.

Outcomes

This data is taken directly from the peer reviewed published paper, and highlights a few key metrics. There are other more complicated conclusions as well.

Weight 

Normal         SupersizeSupersize+ Seaweed
Final Weight g

350

431

348 

Energy Intake kJ/day

38

23

21

Feed conversion efficiency g/Kj   

0.04

0.2

0.03

Fatness

Indicator    Normal      SupersizeSupersize+ Seaweed
Circumference cm 

18.4

20.5

18.9

Abdominal Fat mg/mm     

342

632

337

Total Fat Mass Times 

49

98

53

Bone Density

Indicator Normal     Supersize   Supersize+ Seaweed
Bone Mineral Density  g/cm2

10

12

10

Blood Measures

IndicatorNormal        SupersizeSupersize+ Seaweed
Basal Blood Glucose mmol/L

3.7

4.7

3.6

Total Glucose mmol/L.min

650

800

753

Triglycerides  mmol/L

0.6

1.7

1.3

Systolic Blood Pressure mm

120

136

127

Additional Measures

  • Gut microbiota diversification profiling
  • Metal and metalloid liver analysis
  • Histology
  • Organ weights
  • Body composition
  • Fatty liver disease reversal
  • Gut microbiome reverts to normal
  • Gut inflammation eliminated.
  • Damage to the heart was reversed.

Conclusion

Professor Brown was astonished.  The introduction of seaweed did not reduce the symptoms a little. The seaweed had such a dramatic effect it was if these rats had not eaten the junk food diet. What was going on?

References

  • Wanyonyi, S; du Preez, R; Brown, L; Paul, N; Panchal, S  2017 Kappaphycus alvarezii as a Food Supplement Prevents Diet-Induced Metabolic Syndrome in Rats. Nutrients (9) 11 DOI:10.3390/nu9111261 (Click for Abstract) (Click to download full paper)