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Arthritis Biosea Health Gut Microbiome Health Benefits

Seaweed reduces obesity? Will it save Queensland’s Fattest City?

USQ scientists set to break the obesity cycle with leading edge findings. Are functional foods better than dieting and exercise…..

Toowoomba takes out the unenviable title of the fattest city in Queensland according to researchers at the Mitchell Institute. Over 83% of the Toowoomba population is overweight or obese, posing major disease risk and a potential public health crisis in the region. But all is not lost for the Garden City with one of its locals possibly holding the key to ending the city’s obesity problem. Professor Lindsay Brown of University of Southern Queensland at Toowoomba has spent more than a decade investigating functional foods and their affect on lifestyle diseases such as obesity, high blood pressure and cancer. Professor Brown says that seaweed is showing exceptional effectiveness in reversing obesity related health problems in animal studies and would like to see them in human studies.

Prof Brown and his team of researchers fed rats a junk food diet. The rats, just like humans, gained weight especially around the belly, and also developed fatty liver disease, high blood pressure, pre-type 2 diabetes, arthritis and inflammation of the gut.

But eating as little as 5 gm of seaweed per day completely reversed all of these symptoms.  Blood pressure returned to normal and cell damage to the heart and liver was reversed. Fatty deposits in liver and blood vessels disappeared.  The body’s response to sugar reverted back to the healthy functioning and diabetes risk was eliminated. Inflammation throughout the body was minimised so joint and heart health was much improved.  Professor Brown says the results are highly impressive and somewhat unexpected. He anticipated an improvement in symptoms but not a complete reversal, and a result better than if the patient was taking multiple medicines.

Blood pressure control with seaweed dietary supplement also stopped weight gain
From du Preez 2020 Seaweed reduces weight gain from rats on a junk food diet and makes no different to rats on a standard diet.

Professor Brown now wants to get the message out to the residents of his home town to help change Toowoomba’s frightening health reputation.  He openly provides all the science so residents can judge the effectiveness for themselves. However the media and medical industry have been slow to realise the potential of functional foods.

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Biosea Health Gut Microbiome Health Benefits Reviews

Seaweed Reverses Metabolic Syndrome

Rats fed seaweed reverses metabolic syndrome caused by a junk food diet. Sounds too good to be true?  Professor Brown was astonished. This animal study was published in 2017 but few seem to understand the ramifications.  You can negate a junk food diet with seaweed. Alternatively, you will be able to reverse the ill-health effects of a bad diet.

The Trial

Professor Lindsay Brown University of Southern Queensland supervised this PhD study along with Dr Sunil Pachal at the University of Southern Queensland.  The paper is listed below.

They took rats and fed some of them on an junk food (extra sugar + fat) diet.  Just like in the movie Super Size Me, a 2004 American documentary film directed by and starring Morgan Spurlock. Spurlock’s film follows a 30-day period from February 1 to March 2, 2003, during which he ate only McDonald’s food. The film documents this lifestyle’s drastic effect on Spurlock’s physical and psychological well-being. If you want to see what a human on junk food diet looks like. Or not.

Professor Brown’s trial had 3 groups of 10 rats each.  Group 1 had normal rat diet. Group 2 had a Junk food diet. Group 3 had the junk food diet plus some seaweed (Kappaphycus sp) .  The trial went for 8 weeks.

Outcomes

This data is taken directly from the peer reviewed published paper, and highlights a few key metrics. There are other more complicated conclusions as well.

Seaweed Reverses Metabolic Syndrome:Weight 

Normal          Supersize Supersize+ Seaweed
Final Weight g

350

431

348 

Energy Intake kJ/day

38

23

21

Feed conversion efficiency g/Kj   

0.04

0.2

0.03

Fatness

Indicator     Normal       Supersize Supersize+ Seaweed
Circumference cm 

18.4

20.5

18.9

Abdominal Fat mg/mm     

342

632

337

Total Fat Mass Times 

49

98

53

Bone Density

Indicator  Normal      Supersize    Supersize+ Seaweed
Bone Mineral Density  g/cm2

10

12

10

Blood Measures

Indicator Normal         Supersize Supersize+ Seaweed
Basal Blood Glucose mmol/L

3.7

4.7

3.6

Total Glucose mmol/L.min

650

800

753

Triglycerides  mmol/L

0.6

1.7

1.3

Systolic Blood Pressure mm

120

136

127

NO WEIGHT GAIN. WHY NOT?

blood pressure control with seaweed dietary supplement also stopped any weight gain from junk food
From Wanyonyi 2017. The rats on the junk food + seaweed were no different in weight than the standard diet, in contrast to rats on a junk food diet.

BLOOD GLUCOSE BACK TO NORMAL

blood glucose control with seaweed dietary supplement
From Wanyonyi 2017. Blood glucose controlled with seaweed provided as a dietary supplement.

Additional Measures

  • Gut microbiota diversification profiling
  • Metal and metalloid liver analysis
  • Histology
  • Organ weights
  • Body composition
  • Fatty liver disease reversal
  • Gut microbiome reverts to normal
  • Gut inflammation eliminated.
  • Damage to the heart was reversed.

BLOOD PRESSURE. NO HYPERTENSION

Blood pressure control with seaweed dietary supplement reduces liver inflammatory cells
From du Preez 2020. Seaweed markedly reduces liver inflammatory cells in less than 8 weeks. The damage is completely mitigated by the seaweed.

GUT MICROBIOME CHANGES

gut microbiome changes are the likely reason that blood pressure control with seaweed dietary supplments worked.
Figure from Waynonyi 2017. The microbiome was radically changed with the introduction of Kappaphycus alvarezii to the diets of the junk food animals.

Conclusion

Professor Brown was astonished.  The introduction of seaweed did not reduce the symptoms a little. The seaweed had such a dramatic effect it was if these rats had not eaten the junk food diet. What was going on?

References

[1] Wanyonyi, S; du Preez, R; Brown, L; Paul, N; Panchal, S  2017 Kappaphycus alvarezii as a Food Supplement Prevents Diet-Induced Metabolic Syndrome in Rats. Nutrients (9) 11 DOI:10.3390/nu9111261 (Click for Abstract) (Click to download full paper)